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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP9A All Species: 36.06
Human Site: S287 Identified Species: 66.11
UniProt: O75110 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75110 NP_006036.1 1047 118583 S287 L R S V M N T S N P R S K I G
Chimpanzee Pan troglodytes XP_514727 875 98509 V141 I L F G A L V V V S L V M V A
Rhesus Macaque Macaca mulatta XP_001098852 1044 118009 S284 L R S V M N T S N P R S K I G
Dog Lupus familis XP_534457 1043 118292 S283 L R S V M N T S N P R S K I G
Cat Felis silvestris
Mouse Mus musculus O70228 1047 118590 S287 L R S V M N T S D P R S K I G
Rat Rattus norvegicus XP_002726328 995 111897 Y261 T V V G V V L Y T G R E L R S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509092 1116 127035 S356 L R S V M N T S N P R S K I G
Chicken Gallus gallus XP_417508 1115 125396 S355 L R S V M N T S N P R S K I G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038619 1108 125101 S334 M R S V M N T S Q S K N K V G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396589 1276 146194 S495 T R S L M N H S A P R S K V G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_799223 1105 125600 S345 T R A V M N T S S P R L K F G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P98205 1107 124818 A271 M I D K L T G A I F V F Q I V
Baker's Yeast Sacchar. cerevisiae P40527 1151 130199 T399 R Q A M N T T T A K V K T G L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.5 97.8 97.4 N.A. 97.9 89.7 N.A. 90.2 89.5 N.A. 71.3 N.A. N.A. 54.3 N.A. 60.4
Protein Similarity: 100 83.5 98.2 98.2 N.A. 99.5 91.8 N.A. 92.2 91.5 N.A. 82.4 N.A. N.A. 66.8 N.A. 74.4
P-Site Identity: 100 0 100 100 N.A. 93.3 6.6 N.A. 100 100 N.A. 60 N.A. N.A. 66.6 N.A. 66.6
P-Site Similarity: 100 13.3 100 100 N.A. 100 13.3 N.A. 100 100 N.A. 86.6 N.A. N.A. 80 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 29 44.6 N.A.
Protein Similarity: N.A. N.A. N.A. 48.4 62.7 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 0 8 0 0 8 16 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 8 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 8 0 8 0 8 0 % F
% Gly: 0 0 0 16 0 0 8 0 0 8 0 0 0 8 70 % G
% His: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 8 8 0 0 0 0 0 0 8 0 0 0 0 54 0 % I
% Lys: 0 0 0 8 0 0 0 0 0 8 8 8 70 0 0 % K
% Leu: 47 8 0 8 8 8 8 0 0 0 8 8 8 0 8 % L
% Met: 16 0 0 8 70 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 0 8 70 0 0 39 0 0 8 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 62 0 0 0 0 0 % P
% Gln: 0 8 0 0 0 0 0 0 8 0 0 0 8 0 0 % Q
% Arg: 8 70 0 0 0 0 0 0 0 0 70 0 0 8 0 % R
% Ser: 0 0 62 0 0 0 0 70 8 16 0 54 0 0 8 % S
% Thr: 24 0 0 0 0 16 70 8 8 0 0 0 8 0 0 % T
% Val: 0 8 8 62 8 8 8 8 8 0 16 8 0 24 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _